ANTIOXIDANT AND HEPATOPROTECTIVE EFFECTS OF ASTRAGALUS ECHINOPS AND ASTRAGALUS LOGOPODIOIDES ETHANOLIC EXTRACTS ON PARACETAMOL-INDUCED LIVER INJURY IN RATS
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چکیده
منابع مشابه
The Potential Antioxidant and Hepatoprotective activities of Astragalus subrobustus and Astragalus woronowii ethanolic Extracts against Paracetamol induced Liver Damage in rats
Present study was aimed to investigate in vitro antioxidant and hepatoprotective activities of the ethanolic extracts of Astragalus subrobustus (A. subrobustus) and Astragalus woronowii (A. woronowii) on PCM induced liver damage in rats. The antioxidant activities of both extracts were assayed and their activities were compared to standard antioxidants, ascorbic acid and pyrogallol. Liver injur...
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Ethanolic extract of aerial parts of Sphaeranthus indicus L was investigated for hepatoprotective activity against paracetamol induced liver damage. Various biochemical parameters were studied to evaluate the hepatoprotective activity of ethanolic extract. In serum total bilirubin, total protein, acid phosphatase, aspartate transaminase, alanine transaminase, alkaline phosphatase, γ‐Glutamyl tr...
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The methanol extract of Bauhinia racemosa Lam. (Caesalpiniaceae) stem bark was investigated for the antioxidant and hepatoprotective effects in Wistar albino rats. Different groups of animals were administered with paracetamol (500 mg/kg, (p.o.) once in a day for 7 days) and carbon tetrachloride (CCl4) (30 % CCl4, 1 ml/kg b.wt. in liquid paraffin 3 doses (i.p.) at 72 h interval). The methanol e...
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The hepatoprotective activity of the ethanol extract of Astragalus kahiricus (Fabaceae) roots against ethanol-induced liver apoptosis was evaluated and it showed very promising hepatoprotective actions through different mechanisms. The extract counteracted the ethanol-induced liver enzymes leakage and glutathione depletion. In addition, it demonstrated anti-apoptotic effects against caspase-3 a...
متن کاملHepatoprotective effect of ethanolic extract of Trichosanthes lobata on paracetamol-induced liver toxicity in rats
BACKGROUND Trichosanthes lobata (family cucurbitaceae) is used to treat malarial fever and liver disorders. This study aims to investigate possible hepatoprotective activities of ethanolic extract of Trichosanthes lobata against paracetamol-induced hepatotoxicity. METHODS Hepatotoxicity was induced in Wistar male rats by oral administration, 2 g/kg body weight on 7th day after the administrat...
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ژورنال
عنوان ژورنال: African Journal of Traditional, Complementary and Alternative medicines
سال: 2017
ISSN: 0189-6016,2505-0044
DOI: 10.21010/ajtcam.v14i5.5